[Strategic thinking to improve the basic research in liver transplantation in the new era].

ABSTRACT

Liver transplantation(LT) is the "crown" of surgery and is also an important manifestation of national medical standards. In the past half century, China has made remarkable progress in LT. Currently, China is the second largest country of LT world widely and presents an international advanced level in the efficacy of LT. However, it is notable that there are still many bottlenecks to be solved in China. In the era of precision medicine and big data, the basic research of LT is largely lagging behind and unable to meet the rapid development of clinical needs. Strengthen the basic research of LT is a breakthrough strategy in rejuvenating the country through science and technology in the new era. A high-quality professional research team should be built through multi-disciplinary cooperation and superior resources gathering. Researcher's innovative thinking and strategic vision should be cultivated via the learning of new technologies (e.g., single-cell exploration and multi-omics analysis) and new courses (e.g., transplant oncology and transplant immunology). Government investment also needs to be increased to speed up the nurturing of high-level talents and get great achievements. Basic research is the driving force for China to become a leading country in LT.