A prospective multicentre external validation study of the Liverpool Peritonsillar abscess Score (LPS) with a no-examination COVID-19 modification.
Clin Otolaryngol
; 46(1): 229-233, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-32997893
ABSTRACT
OBJECTIVES:
Our primary aim was to validate the Liverpool Peritonsillar abscess Score (LPS) externally in a new patient cohort. Our secondary aim was to modify the LPS in the light of the COVID-19 pandemic to produce a no-examination variant for use in this instance.DESIGN:
Prospective multicentre external validation study.SETTING:
Six different secondary care institutions across the United Kingdom.PARTICIPANTS:
Patients over 16 years old who were referred to ENT with any uncomplicated sore throat such a tonsillitis or peritonsillar abscess (PTA). MAIN OUTCOMEMEASURES:
Sensitivity, specificity, positive predictive value and negative predictive value for both the original LPS model and the modified model for COVID-19.RESULTS:
The LPS model had sensitivity and specificity calculated at 98% and 79%, respectively. The LPS has a high negative predictive value (NPV) of 99%. The positive predictive value (PPV) was slightly lower at 63%. Receiver operating characteristic (ROC) curve, including the area under the curve (AUROC), was 0.888 which indicates very good accuracy.CONCLUSIONS:
External validation of the LPS against an independent geographically diverse population yields high NPV. This may support non-specialist colleagues who may have concerns about mis-diagnosing a PTA. The COVID-19 modification of the LPS has a similar NPV, which may be of use where routine oral examination is to be avoided during the COVID-19 pandemic.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Abscesso Peritonsilar
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Gerenciamento Clínico
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Pandemias
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SARS-CoV-2
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COVID-19
Tipo de estudo:
Clinical_trials
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article