In-hospital cardiac arrest in critically ill patients with covid-19: multicenter cohort study.
BMJ
; 371: m3513, 2020 09 30.
Article
em En
| MEDLINE
| ID: mdl-32998872
ABSTRACT
OBJECTIVES:
To estimate the incidence, risk factors, and outcomes associated with in-hospital cardiac arrest and cardiopulmonary resuscitation in critically ill adults with coronavirus disease 2019 (covid-19).DESIGN:
Multicenter cohort study.SETTING:
Intensive care units at 68 geographically diverse hospitals across the United States.PARTICIPANTS:
Critically ill adults (age ≥18 years) with laboratory confirmed covid-19. MAIN OUTCOMEMEASURES:
In-hospital cardiac arrest within 14 days of admission to an intensive care unit and in-hospital mortality.RESULTS:
Among 5019 critically ill patients with covid-19, 14.0% (701/5019) had in-hospital cardiac arrest, 57.1% (400/701) of whom received cardiopulmonary resuscitation. Patients who had in-hospital cardiac arrest were older (mean age 63 (standard deviation 14) v 60 (15) years), had more comorbidities, and were more likely to be admitted to a hospital with a smaller number of intensive care unit beds compared with those who did not have in-hospital cardiac arrest. Patients who received cardiopulmonary resuscitation were younger than those who did not (mean age 61 (standard deviation 14) v 67 (14) years). The most common rhythms at the time of cardiopulmonary resuscitation were pulseless electrical activity (49.8%, 199/400) and asystole (23.8%, 95/400). 48 of the 400 patients (12.0%) who received cardiopulmonary resuscitation survived to hospital discharge, and only 7.0% (28/400) survived to hospital discharge with normal or mildly impaired neurological status. Survival to hospital discharge differed by age, with 21.2% (11/52) of patients younger than 45 years surviving compared with 2.9% (1/34) of those aged 80 or older.CONCLUSIONS:
Cardiac arrest is common in critically ill patients with covid-19 and is associated with poor survival, particularly among older patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Mortalidade Hospitalar
/
Infecções por Coronavirus
/
Betacoronavirus
/
Parada Cardíaca
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País como assunto:
America do norte
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article