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Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation.
Guglielmi, Paolo; Rotondi, Giulia; Secci, Daniela; Angeli, Andrea; Chimenti, Paola; Nocentini, Alessio; Bonardi, Alessandro; Gratteri, Paola; Carradori, Simone; Supuran, Claudiu T.
Afiliação
  • Guglielmi P; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, Rome, Italy.
  • Rotondi G; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, Rome, Italy.
  • Secci D; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, Rome, Italy.
  • Angeli A; Neurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Sesto Fiorentino, Italy.
  • Chimenti P; Centre of Advanced Research in Bionanoconjugates and Biopolymers Department, "Petru Poni" Institute of Macromolecular Chemistry, Iasi, Romania.
  • Nocentini A; Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, Rome, Italy.
  • Bonardi A; Neurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Sesto Fiorentino, Italy.
  • Gratteri P; Neurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, Laboratory of Molecular Modeling Cheminformatics & QSAR University of Florence, Sesto Fiorentino Italy.
  • Carradori S; Neurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, Sesto Fiorentino, Italy.
  • Supuran CT; Neurofarba Department, Section of Pharmaceutical and Nutraceutical Sciences, Laboratory of Molecular Modeling Cheminformatics & QSAR University of Florence, Sesto Fiorentino Italy.
J Enzyme Inhib Med Chem ; 35(1): 1891-1905, 2020 Dec.
Article em En | MEDLINE | ID: mdl-33003975
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacarina / Edulcorantes / Tiazinas / Inibidores da Anidrase Carbônica / Anidrases Carbônicas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sacarina / Edulcorantes / Tiazinas / Inibidores da Anidrase Carbônica / Anidrases Carbônicas Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article