EFTUD2 maintains the survival of tumor cells and promotes hepatocellular carcinoma progression via the activation of STAT3.

Tu, Mengxian; He, Lu; You, Yang; Li, Jinying; Yao, Nan; Qu, Chen; Huang, Wei; Xu, Leibo; Luo, Rongcheng; Hong, Jian

Tu, Mengxian; He, Lu; You, Yang; Li, Jinying; Yao, Nan; Qu, Chen; Huang, Wei; Xu, Leibo; Luo, Rongcheng; Hong, Jian.

Afiliação

Tu M; Department of Pathophysiology, School of Medicine, Jinan University, 510630, Guangzhou, Guangdong, China.
He L; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation and Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 510120, Guangzhou, Guangdong, China.
You Y; Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, 510315, Guangzhou, Guangdong, China.
Li J; Department of Radiotherapy, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, 510095, Guangzhou, Guangdong, China.
Yao N; Department of Pathophysiology, School of Medicine, Jinan University, 510630, Guangzhou, Guangdong, China.
Qu C; Department of Gastroenterology, The First Affiliated Hospital of Jinan University, 510630, Guangzhou, Guangdong, China.
Huang W; Department of Pathophysiology, School of Medicine, Jinan University, 510630, Guangzhou, Guangdong, China.
Xu L; Department of Pathophysiology, School of Medicine, Jinan University, 510630, Guangzhou, Guangdong, China.
Luo R; Department of Gastroenterology, The First Affiliated Hospital of Jinan University, 510630, Guangzhou, Guangdong, China.
Hong J; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation and Department of Biliary-Pancreatic Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 510120, Guangzhou, Guangdong, China.

Cell Death Dis ; 11(10): 830, 2020 10 06.

Article em En | MEDLINE | ID: mdl-33024090

Assuntos

Carcinoma Hepatocelular/patologia; Neoplasias Hepáticas/patologia; Fatores de Alongamento de Peptídeos/metabolismo; Ribonucleoproteína Nuclear Pequena U5/metabolismo; Fator de Transcrição STAT3/metabolismo; Animais; Carcinoma Hepatocelular/genética; Linhagem Celular Tumoral; Movimento Celular/genética; Proliferação de Células/fisiologia; Transição Epitelial-Mesenquimal/genética; Regulação Neoplásica da Expressão Gênica/genética; Humanos; Neoplasias Hepáticas/genética; Camundongos; Fatores de Alongamento de Peptídeos/genética; Ribonucleoproteína Nuclear Pequena U5/genética; Fator de Transcrição STAT3/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Alongamento de Peptídeos / Ribonucleoproteína Nuclear Pequena U5 / Carcinoma Hepatocelular / Fator de Transcrição STAT3 / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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