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Meta-Analysis on the Efficacy and Safety of Laparoscopic Surgery for Large Gastric Gastrointestinal Stromal Tumors.
Yu, Miao; Wang, Deng-Chao; Wei, Jian; Lei, Yue-Hua; Fu, Zhao-Jun; Yang, Yu-Hui.
Afiliação
  • Yu M; Department of Basic Medicine, Sichuan Vocational College of Health and Rehabilitation, Zigong, Sichuan, China.
  • Wang DC; Department of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, China.
  • Wei J; Department of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, China.
  • Lei YH; Department of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, China.
  • Fu ZJ; Department of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, China.
  • Yang YH; Department of General Surgery, Zigong Fourth People's Hospital, Zigong, Sichuan, China.
Am Surg ; 87(3): 450-457, 2021 Mar.
Article em En | MEDLINE | ID: mdl-33026232
ABSTRACT

BACKGROUND:

The aim of this study was to conduct a meta-analysis comparing the safety and feasibility of laparoscopic versus open resection for gastric gastrointestinal stromal tumors (GISTs) larger than 5 cm.

METHOD:

We searched the Cochrane Library, PubMed, and Embase for relevant articles. Randomized and nonrandomized clinical trials were identified and included in this study. Searching for related articles on large GIST (>5 cm) for laparoscopic resection (laparoscopic group [LAPG]) and open resection (open group [OG]), RevMan 5.3 was used for data analysis, comparing 2 groups of operation time, intraoperative blood loss, complications, length of hospital stay, recurrence rate, disease-free survival, and overall survival.

RESULTS:

Seven studies including 440 patients were identified for the meta-analysis. Meta-analysis revealed that LAPG had less bleeding, shorter postoperative hospital stay, and a better 5-year disease-free survival. There was no significant difference between LAPG and OG in operation time, postoperative complications, recurrence rate, and overall survival.

CONCLUSION:

Laparoscopic resection of large (>5 cm) GIST is safe and feasible and has the advantages of less intraoperative blood loss and fast postoperative recovery, with a good outcome in the recent oncology.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Laparoscopia / Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Tipo de estudo: Clinical_trials / Etiology_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Laparoscopia / Tumores do Estroma Gastrointestinal / Neoplasias Gastrointestinais Tipo de estudo: Clinical_trials / Etiology_studies / Systematic_reviews Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article