Cortico-spinal imaging to study pain.
Neuroimage
; 224: 117439, 2021 01 01.
Article
em En
| MEDLINE
| ID: mdl-33039624
ABSTRACT
Functional magnetic resonance imaging of the brain has helped to reveal mechanisms of pain perception in health and disease. Recently, imaging approaches have been developed that allow recording neural activity simultaneously in the brain and in the spinal cord. These approaches offer the possibility to examine pain perception in the entire central pain system and in addition, to investigate cortico-spinal interactions during pain processing. Although cortico-spinal imaging is a promising technique, it bears challenges concerning data acquisition and data analysis strategies. In this review, we discuss studies that applied simultaneous imaging of the brain and spinal cord to explore central pain processing. Furthermore, we describe different MR-related acquisition techniques, summarize advantages and disadvantages of approaches that have been implemented so far and present software that has been specifically developed for the analysis of spinal fMRI data to address challenges of spinal data analysis.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Dor
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Medula Espinal
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Processamento de Imagem Assistida por Computador
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Imageamento por Ressonância Magnética
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Córtex Cerebral
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Neuroimagem Funcional
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article