Carnosine synthase deficiency is compatible with normal skeletal muscle and olfactory function but causes reduced olfactory sensitivity in aging mice.

Wang-Eckhardt, Lihua; Bastian, Asisa; Bruegmann, Tobias; Sasse, Philipp; Eckhardt, Matthias

Wang-Eckhardt, Lihua; Bastian, Asisa; Bruegmann, Tobias; Sasse, Philipp; Eckhardt, Matthias.

Afiliação

Wang-Eckhardt L; Institute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany.
Bastian A; Institute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany.
Bruegmann T; Institute of Physiology I, Medical Faculty, University of Bonn, Bonn, Germany.
Sasse P; Institute of Physiology I, Medical Faculty, University of Bonn, Bonn, Germany.
Eckhardt M; Institute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany. Electronic address: eckhardt@uni-bonn.de.

J Biol Chem ; 295(50): 17100-17113, 2020 12 11.

Article em En | MEDLINE | ID: mdl-33040025

Assuntos

Envelhecimento/metabolismo; Carnosina/metabolismo; Contração Muscular; Peptídeo Sintases/deficiência; Receptores Odorantes/metabolismo; Envelhecimento/genética; Animais; Carnosina/genética; Camundongos; Camundongos Knockout; Músculo Esquelético; Peptídeo Sintases/metabolismo; Receptores Odorantes/genética

Palavras-chave

aging; anserine; carnosine; histidine-containing dipeptide (HSD); neurochemistry; neuropeptide; neuroscience; olfaction; olfactory epithelium (OE); olfactory receptor neuron (ORN); peptides

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeo Sintases / Envelhecimento / Carnosina / Receptores Odorantes / Contração Muscular Tipo de estudo: Diagnostic_studies / Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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