Inositol-Requiring Kinase 1 Regulates Apoptosis via Inducing Endoplasmic Reticulum Stress in Colitis Epithelial Cells.

Zhang, Bei; Su, XiaoYan; Xie, ZhengYuan; Ding, Hao; Wang, Ting; Xie, RuYi; Wen, ZhiLi

Zhang, Bei; Su, XiaoYan; Xie, ZhengYuan; Ding, Hao; Wang, Ting; Xie, RuYi; Wen, ZhiLi.

Afiliação

Zhang B; The Department of Gastroenterology, Second Hospital Affiliated to Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Su X; The Department of Pathology, Second Hospital Affiliated to Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Xie Z; The Department of Gastroenterology, Second Hospital Affiliated to Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Ding H; The Department of Gastroenterology, Second Hospital Affiliated to Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Wang T; The Department of Gastroenterology, First Hospital Affiliated to Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Xie R; The Department of Gastroenterology, Second Hospital Affiliated to Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China.
Wen Z; The Department of Gastroenterology, Second Hospital Affiliated to Nanchang University, No. 1 Minde Road, Nanchang, 330006, Jiangxi, People's Republic of China. stayfy2000@163.com.

Dig Dis Sci ; 66(9): 3015-3025, 2021 09.

Article em En | MEDLINE | ID: mdl-33043405

Assuntos

Colite Ulcerativa; Estresse do Retículo Endoplasmático/genética; Retículo Endoplasmático/fisiologia; Endorribonucleases; Proteínas Serina-Treonina Quinases; Resposta a Proteínas não Dobradas; Apoptose; Caspase 12/genética; Linhagem Celular; Proliferação de Células; Sobrevivência Celular; Colite Ulcerativa/metabolismo; Colite Ulcerativa/patologia; Endorribonucleases/genética; Endorribonucleases/metabolismo; Perfilação da Expressão Gênica/métodos; Regulação da Expressão Gênica; Humanos; Interleucina-6/metabolismo; Mucosa Intestinal/metabolismo; Proteínas Serina-Treonina Quinases/genética; Proteínas Serina-Treonina Quinases/metabolismo; Proteína 1 de Ligação a X-Box/genética

Palavras-chave

Apoptosis; Endoplasmic reticulum stress; Inositol-requiring kinase 1; Interleukin 6; Ulcerative colitis; Unfolded protein response

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colite Ulcerativa / Proteínas Serina-Treonina Quinases / Retículo Endoplasmático / Endorribonucleases / Resposta a Proteínas não Dobradas / Estresse do Retículo Endoplasmático Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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