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Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics.
Ghoussaini, Maya; Mountjoy, Edward; Carmona, Miguel; Peat, Gareth; Schmidt, Ellen M; Hercules, Andrew; Fumis, Luca; Miranda, Alfredo; Carvalho-Silva, Denise; Buniello, Annalisa; Burdett, Tony; Hayhurst, James; Baker, Jarrod; Ferrer, Javier; Gonzalez-Uriarte, Asier; Jupp, Simon; Karim, Mohd Anisul; Koscielny, Gautier; Machlitt-Northen, Sandra; Malangone, Cinzia; Pendlington, Zoe May; Roncaglia, Paola; Suveges, Daniel; Wright, Daniel; Vrousgou, Olga; Papa, Eliseo; Parkinson, Helen; MacArthur, Jacqueline A L; Todd, John A; Barrett, Jeffrey C; Schwartzentruber, Jeremy; Hulcoop, David G; Ochoa, David; McDonagh, Ellen M; Dunham, Ian.
Afiliação
  • Ghoussaini M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • Mountjoy E; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Carmona M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • Peat G; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Schmidt EM; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Hercules A; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Fumis L; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Miranda A; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Carvalho-Silva D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • Buniello A; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Burdett T; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Hayhurst J; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Baker J; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Ferrer J; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Gonzalez-Uriarte A; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Jupp S; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Karim MA; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Koscielny G; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Machlitt-Northen S; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Malangone C; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Pendlington ZM; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Roncaglia P; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Suveges D; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Wright D; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Vrousgou O; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Papa E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Parkinson H; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • MacArthur JAL; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Todd JA; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Barrett JC; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Schwartzentruber J; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Hulcoop DG; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Ochoa D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.
  • McDonagh EM; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
  • Dunham I; Open Targets, Wellcome Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK.
Nucleic Acids Res ; 49(D1): D1311-D1320, 2021 01 08.
Article em En | MEDLINE | ID: mdl-33045747
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Software / Doenças Inflamatórias Intestinais / Genoma Humano / Bases de Dados Genéticas / Locos de Características Quantitativas / Terapia de Alvo Molecular Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Software / Doenças Inflamatórias Intestinais / Genoma Humano / Bases de Dados Genéticas / Locos de Características Quantitativas / Terapia de Alvo Molecular Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article