Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish.

Okamoto, Ryuji; Goto, Itaru; Nishimura, Yuhei; Kobayashi, Issei; Hashizume, Ryotaro; Yoshida, Yoshinori; Ito, Rie; Kobayashi, Yuhko; Nishikawa, Misato; Ali, Yusuf; Saito, Shunsuke; Tanaka, Toshio; Sawa, Yoshiki; Ito, Masaaki; Dohi, Kaoru

Okamoto, Ryuji; Goto, Itaru; Nishimura, Yuhei; Kobayashi, Issei; Hashizume, Ryotaro; Yoshida, Yoshinori; Ito, Rie; Kobayashi, Yuhko; Nishikawa, Misato; Ali, Yusuf; Saito, Shunsuke; Tanaka, Toshio; Sawa, Yoshiki; Ito, Masaaki; Dohi, Kaoru.

Afiliação

Okamoto R; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Goto I; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Nishimura Y; Department of Molecular and Cellular Pharmacology, Pharmacogenomics and Pharmacoinformatics, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Kobayashi I; Core-Lab, Graduate School of Regional Innovation Studies, Mie University, Tsu, Mie, Japan.
Hashizume R; Department of Pathology and Matrix Biology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Yoshida Y; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto, Japan.
Ito R; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Kobayashi Y; Core-Lab, Graduate School of Regional Innovation Studies, Mie University, Tsu, Mie, Japan.
Nishikawa M; Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto, Japan.
Ali Y; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Saito S; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tanaka T; Department of Molecular and Cellular Pharmacology, Pharmacogenomics and Pharmacoinformatics, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Sawa Y; Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Ito M; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.
Dohi K; Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu, Mie, Japan.

PLoS One ; 15(10): e0240129, 2020.

Article em En | MEDLINE | ID: mdl-33048975

Assuntos

Cardiomiopatia Hipertrófica Familiar/genética; Conexinas/genética; Infarto do Miocárdio/patologia; Miocárdio/patologia; Adulto; Substituição de Aminoácidos; Angiotensina II/toxicidade; Animais; Animais Geneticamente Modificados; Células COS; Cardiomiopatia Hipertrófica Familiar/diagnóstico; Cardiomiopatia Hipertrófica Familiar/patologia; Cardiomiopatia Hipertrófica Familiar/cirurgia; Criança; Chlorocebus aethiops; Conexina 43/metabolismo; Conexinas/metabolismo; Análise Mutacional de DNA; Modelos Animais de Doenças; Doxorrubicina/toxicidade; Feminino; Junções Comunicantes/patologia; Técnicas de Inativação de Genes; Testes Genéticos; Transplante de Coração; Humanos; Células-Tronco Pluripotentes Induzidas; Masculino; Camundongos; Infarto do Miocárdio/etiologia; Miocárdio/citologia; Miócitos Cardíacos; Linhagem; Cultura Primária de Células; Domínios Proteicos/genética; Ratos; Peixe-Zebra; Proteínas de Peixe-Zebra/genética; Proteínas de Peixe-Zebra/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Conexinas / Cardiomiopatia Hipertrófica Familiar / Infarto do Miocárdio / Miocárdio Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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