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The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier.
Buzhdygan, Tetyana P; DeOre, Brandon J; Baldwin-Leclair, Abigail; Bullock, Trent A; McGary, Hannah M; Khan, Jana A; Razmpour, Roshanak; Hale, Jonathan F; Galie, Peter A; Potula, Raghava; Andrews, Allison M; Ramirez, Servio H.
Afiliação
  • Buzhdygan TP; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Center for Substance Abuse Research, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • DeOre BJ; Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, United States of America.
  • Baldwin-Leclair A; Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, United States of America.
  • Bullock TA; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Center for Substance Abuse Research, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • McGary HM; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Khan JA; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Razmpour R; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Hale JF; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Galie PA; Department of Biomedical Engineering, Rowan University, Glassboro, NJ 08028, United States of America.
  • Potula R; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Center for Substance Abuse Research, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Andrews AM; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Center for Substance Abuse Research, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America.
  • Ramirez SH; Department of Pathology and Laboratory Medicine, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Center for Substance Abuse Research, The Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, United States of America; Th
Neurobiol Dis ; 146: 105131, 2020 12.
Article em En | MEDLINE | ID: mdl-33053430
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Permeabilidade Capilar / Barreira Hematoencefálica / Metaloproteinases da Matriz / Células Endoteliais / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / Inflamação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Permeabilidade Capilar / Barreira Hematoencefálica / Metaloproteinases da Matriz / Células Endoteliais / Glicoproteína da Espícula de Coronavírus / Enzima de Conversão de Angiotensina 2 / SARS-CoV-2 / Inflamação Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article