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Low mortality of hospitalised patients with COVID-19 in a tertiary Danish hospital setting.
Madsen, Lone Wulff; Lindvig, Susan Olaf; Rasmussen, Line Dahlerup; Knudtzen, Fredrikke Christie; Laursen, Christian B; Øvrehus, Anne; Nielsen, Stig Lønberg; Johansen, Isik Somuncu.
Afiliação
  • Madsen LW; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark; OPEN, Open Patient data Explorative Network, Odense University Hospital, University of Southern Denmark, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Electronic addre
  • Lindvig SO; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark. Electronic address: Susan.Olaf.Lindvig@rsyd.dk.
  • Rasmussen LD; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark. Electronic address: Line.Dahlerup.Rasmussen@rsyd.dk.
  • Knudtzen FC; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Clinical Center of Emerging and Vector-borne Infections, Odense University Hospital, Denmark. Electronic address: Fredrikke.Christie.Knudt
  • Laursen CB; Department of Clinical Research, University of Southern Denmark, Odense, Denmark; Department of Respiratory Medicine, Odense University Hospital, Denmark. Electronic address: Christian.B.Laursen@rsyd.dk.
  • Øvrehus A; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Electronic address: Anne.Oevrehus@rsyd.dk.
  • Nielsen SL; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark. Electronic address: stig.nielsen@rsyd.dk.
  • Johansen IS; Department of Infectious Diseases, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark. Electronic address: Isik.Somuncu.Johansen@rsyd.dk.
Int J Infect Dis ; 102: 212-219, 2021 Jan.
Article em En | MEDLINE | ID: mdl-33059095
ABSTRACT

OBJECTIVES:

We aimed to describe clinical characteristics and outcomes of admitted COVID-19 patients in a Danish hospital setting where an early active government intervention was taken.

METHODS:

Prospective cohort study including all admitted patients to the COVID-19 unit at Odense University Hospital from March 10 to April 21, 2020. Patients were assessed by a multidisciplinary team at admission. Outcome parameters were development of acute respiratory distress syndrome (ARDS), intensive care unit (ICU) admission, death and admission time.

RESULTS:

We included 83 patients (median age 62 years, 62.7% male). At hospitalization, 31.3% needed oxygen supplementation and the median National Early Warning Score was four. Median admission time was 7 days (Interquartile ranges (IQR) 3-12). In total, ARDS was diagnosed in 33.7% (28/83) of the patients corresponding to an incidence rate of 7.1 per 100 person days (95% CI 4.1-10.2). Overall 13 patients (15.7%) were transferred to the ICU of whom 11 (84.6%) received corticosteroids.. No patients died while admitted to the ICU. Four patients (4.8%) died during admission.

CONCLUSION:

Despite similar patient characteristics compared to those reported by others, we found a low overall mortality of < 5%.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País como assunto: Europa Idioma: En Ano de publicação: 2021 Tipo de documento: Article