Effects of proprotein convertase subtilisin/kexin type 9 and nilotinib plasma concentrations on nilotinib-induced hypercholesterolaemia in patients with chronic myeloid leukaemia.

Abumiya, Maiko; Akamine, Yumiko; Sato, Shiori; Takahashi, Saori; Yoshioka, Tomoko; Kameoka, Yoshihiro; Takahashi, Naoto; Miura, Masatomo

Abumiya, Maiko; Akamine, Yumiko; Sato, Shiori; Takahashi, Saori; Yoshioka, Tomoko; Kameoka, Yoshihiro; Takahashi, Naoto; Miura, Masatomo.

Afiliação

Abumiya M; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Akamine Y; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Sato S; Department of Pharmacy, Akita University Hospital, Akita, Japan.
Takahashi S; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Yoshioka T; Clinical Research Promotion and Support Center, Akita University Hospital, Akita, Japan.
Kameoka Y; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Takahashi N; Department of Hematology, Nephrology, and Rheumatology, Akita University Graduate School of Medicine, Akita, Japan.
Miura M; Clinical Research Promotion and Support Center, Akita University Hospital, Akita, Japan.

J Clin Pharm Ther ; 46(2): 382-387, 2021 Apr.

Article em En | MEDLINE | ID: mdl-33108009

Assuntos

Antineoplásicos/efeitos adversos; Hipercolesterolemia/induzido quimicamente; Leucemia Mielogênica Crônica BCR-ABL Positiva/tratamento farmacológico; Pró-Proteína Convertase 9/sangue; Pirimidinas/efeitos adversos; Adulto; Idoso; Antineoplásicos/uso terapêutico; LDL-Colesterol/efeitos dos fármacos; Cromatografia Líquida de Alta Pressão; Ensaio de Imunoadsorção Enzimática; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Pirimidinas/sangue; Pirimidinas/uso terapêutico; Estudos Retrospectivos

Palavras-chave

low-density lipoprotein cholesterol; nilotinib; plasma trough concentration; proprotein convertase subtilisin/kexin type 9

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Leucemia Mielogênica Crônica BCR-ABL Positiva / Pró-Proteína Convertase 9 / Hipercolesterolemia / Antineoplásicos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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