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A protein tertiary structure mimetic modulator of the Hippo signalling pathway.
Adihou, Hélène; Gopalakrishnan, Ranganath; Förster, Tim; Guéret, Stéphanie M; Gasper, Raphael; Geschwindner, Stefan; Carrillo García, Carmen; Karatas, Hacer; Pobbati, Ajaybabu V; Vazquez-Chantada, Mercedes; Davey, Paul; Wassvik, Carola M; Pang, Jeremy Kah Sheng; Soh, Boon Seng; Hong, Wanjin; Chiarparin, Elisabetta; Schade, Dennis; Plowright, Alleyn T; Valeur, Eric; Lemurell, Malin; Grossmann, Tom N; Waldmann, Herbert.
Afiliação
  • Adihou H; Medicinal Chemistry, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Gopalakrishnan R; AstraZeneca-MPI Satellite Unit, Dortmund, Germany.
  • Förster T; Medicinal Chemistry, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Guéret SM; AstraZeneca-MPI Satellite Unit, Dortmund, Germany.
  • Gasper R; AstraZeneca-MPI Satellite Unit, Dortmund, Germany.
  • Geschwindner S; Medicinal Chemistry, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Carrillo García C; AstraZeneca-MPI Satellite Unit, Dortmund, Germany.
  • Karatas H; Max Planck Institute for Molecular Physiology, Dortmund, Germany.
  • Pobbati AV; Structure & Biophysics, Discovery Sciences, R&D, AstraZeneca, Gothenburg, Sweden.
  • Vazquez-Chantada M; Department of Pharmaceutical and Medicinal Chemistry, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Davey P; Max Planck Institute for Molecular Physiology, Dortmund, Germany.
  • Wassvik CM; Department of Multi-Modal Molecular (M3) Biology, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.
  • Pang JKS; Mechanistic Biology & Profiling, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.
  • Soh BS; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Hong W; Medicinal Chemistry, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
  • Chiarparin E; Disease Modelling and Therapeutics Laboratory, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.
  • Schade D; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
  • Plowright AT; Disease Modelling and Therapeutics Laboratory, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.
  • Valeur E; Department of Biological Sciences, National University of Singapore, Singapore, Singapore.
  • Lemurell M; Key Laboratory for Major Obstetric Diseases of Guangdong Province, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
  • Grossmann TN; Department of Multi-Modal Molecular (M3) Biology, A*STAR Institute of Molecular and Cell Biology, Singapore, Singapore.
  • Waldmann H; Medicinal Chemistry, Oncology R&D, AstraZeneca, Cambridge, UK.
Nat Commun ; 11(1): 5425, 2020 10 27.
Article em En | MEDLINE | ID: mdl-33110077
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Peptidomiméticos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Peptidomiméticos Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article