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Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.
Goetzman, Eric S; Bharathi, Sivakama S; Zhang, Yuxun; Zhao, Xue-Jun; Dobrowolski, Steven F; Peasley, Kevin; Sims-Lucas, Sunder; Monga, Satdarshan P.
Afiliação
  • Goetzman ES; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. eric.goetzman@chp.edu.
  • Bharathi SS; Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. eric.goetzman@chp.edu.
  • Zhang Y; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Zhao XJ; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Dobrowolski SF; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Peasley K; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Sims-Lucas S; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Monga SP; Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sci Rep ; 10(1): 18367, 2020 10 27.
Article em En | MEDLINE | ID: mdl-33110171
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Sirtuínas / Ácidos Graxos / Hepatopatia Gordurosa não Alcoólica Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Sirtuínas / Ácidos Graxos / Hepatopatia Gordurosa não Alcoólica Limite: Animals Idioma: En Ano de publicação: 2020 Tipo de documento: Article