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Retrotrigonal muscular layer sling associated with total anatomical reconstruction in robot-assisted radical prostatectomy and early continence.
Zanoni, Matteo Luigi; Grizzi, Fabio; Maffei, Davide; Vota, Paolo; Frego, Nicola; Toia, Giovanni; Mazzieri, Cinzia; Lazzeri, Massimo; Buffi, Nicolò; Lughezzani, Giovanni; Casale, Paolo; Saita, Alberto; Guazzoni, Giorgio; Mandressi, Alberto; Taverna, Gianluigi.
Afiliação
  • Zanoni ML; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
  • Grizzi F; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Maffei D; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Vota P; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
  • Frego N; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Toia G; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
  • Mazzieri C; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
  • Lazzeri M; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
  • Buffi N; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Lughezzani G; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Casale P; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
  • Saita A; Humanitas Clinical and Research Center, IRCCS, via Manzoni 56, 20089, Rozzano, Italy.
  • Guazzoni G; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20090, Milan, Pieve Emanuele, Italy.
  • Mandressi A; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy.
  • Taverna G; Department of Urology, Humanitas Mater Domini, Via Gerenzano 2, 21053, Varese, Castellanza, Italy. gianluigi.taverna@humanitas.it.
World J Urol ; 39(7): 2475-2481, 2021 Jul.
Article em En | MEDLINE | ID: mdl-33112984
BACKGROUND AND PURPOSE: Urinary continence (UC) represents the main non-oncological goal in patients undergoing robotic-assisted radical prostatectomy (RARP). To evaluate the efficacy in early UC achievement, we described a new sling technique using the retrotrigonal muscular layer (TZ sling) combined with total anatomical reconstruction (TAR). PATIENTS AND METHODS: We prospectively enrolled 407 consecutive prostate cancer (PC) patients undergoing RARP between May 2017 and January 2020. The first 250 patients underwent only TAR, while the following 157 patients TAR + TZ sling, by isolating and anchoring the retrotrigonal muscular layer to the pubic bone with 2 bilateral sutures. We defined UC as ≤ 1 pad/die, which was assessed after catheter removal at 1, 4 and 12wk using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score. Sling-related operative time and post-operative complications were analyzed. RESULTS: In the TAR group, the UC rates at the 1, 4 and 12wk were 58%, 66% and 86%; in the TAR + TZ sling group 72%, 76% and 88%, respectively. A statistically significant difference was observed in the two groups at 1wk (p = 0.0049) and 4wk (p = 0.035) favoring the TZ sling surgical strategy. This difference in UC rates was lost at 12wk (p ≥ 0.05). No statistically significant differences in operative time, acute urinary retentions and other complication rates were observed between the two groups (p = NS). CONCLUSIONS: We have described a new, safe, feasible modification of RARP using a sling with the retrotrigonal muscular layer associated with TAR. We have demonstrated a statistically significant improvement in early UC rate in patients who are undergoing TAR and TZ sling compared to undergoing only TAR.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Próstata / Prostatectomia / Neoplasias da Próstata / Procedimentos Cirúrgicos Robóticos / Músculo Liso Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Próstata / Prostatectomia / Neoplasias da Próstata / Procedimentos Cirúrgicos Robóticos / Músculo Liso Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Aged / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article