Improvement of DC-based vaccines using adjuvant TLR4-binding 60S acidic ribosomal protein P2 and immune checkpoint inhibitors.

Jang, Gun-Young; Kim, Young Seob; Lee, Sung Eun; Lee, Ji Won; Han, Hee Dong; Kang, Tae Heung; Park, Yeong-Min

Jang, Gun-Young; Kim, Young Seob; Lee, Sung Eun; Lee, Ji Won; Han, Hee Dong; Kang, Tae Heung; Park, Yeong-Min.

Afiliação

Jang GY; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea.
Kim YS; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea.
Lee SE; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea.
Lee JW; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea.
Han HD; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea.
Kang TH; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea. kangiron@kku.ac.kr.
Park YM; Department of Immunology, College of Medicine, Konkuk University, 268 Chungwon-daero Chungju-si Chungcheongbuk-do 27478, Seoul, South Korea. immun3023@kku.ac.kr.

Cancer Immunol Immunother ; 70(4): 1075-1088, 2021 Apr.

Article em En | MEDLINE | ID: mdl-33113002

Assuntos

Vacinas Anticâncer/administração & dosagem; Células Dendríticas/imunologia; Inibidores de Checkpoint Imunológico/farmacologia; Proteínas Ribossômicas/metabolismo; Timoma/terapia; Receptor 4 Toll-Like/metabolismo; Neoplasias do Colo do Útero/terapia; Adjuvantes Imunológicos; Animais; Apoptose; Vacinas Anticâncer/imunologia; Proliferação de Células; Feminino; Humanos; Imunoterapia; Camundongos; Camundongos Endogâmicos C57BL; Ligação Proteica; Timoma/imunologia; Timoma/patologia; Neoplasias do Timo/imunologia; Neoplasias do Timo/patologia; Neoplasias do Timo/terapia; Células Tumorais Cultivadas; Neoplasias do Colo do Útero/imunologia; Neoplasias do Colo do Útero/patologia; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

60S acidic ribosomal protein P2 (RPLP2); Cancer immunotherapy; DC-based vaccine; Immune checkpoint inhibitor; Toll-like receptor 4

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Ribossômicas / Timoma / Células Dendríticas / Neoplasias do Colo do Útero / Vacinas Anticâncer / Receptor 4 Toll-Like / Inibidores de Checkpoint Imunológico Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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