Colon-specific tablets containing 5-fluorouracil microsponges for colon cancer targeting.

Othman, Mahmoud H; Zayed, Gamal M; Ali, Usama F; Abdellatif, Ahmed A H

Othman, Mahmoud H; Zayed, Gamal M; Ali, Usama F; Abdellatif, Ahmed A H.

Afiliação

Othman MH; Department of Physical Pharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.
Zayed GM; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Ali UF; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.
Abdellatif AAH; Al-Azhar Centre of Nanosciences and Applications (ACNA), Al-Azhar University, Assiut, Egypt.

Drug Dev Ind Pharm ; 46(12): 2081-2088, 2020 Dec.

Article em En | MEDLINE | ID: mdl-33135492

Assuntos

Colo/fisiopatologia; Neoplasias do Colo; Fluoruracila; Neoplasias do Colo/tratamento farmacológico; Sistemas de Liberação de Medicamentos; Humanos; Comprimidos; Comprimidos com Revestimento Entérico

Palavras-chave

5-fluorouracil (5-FU); Colon targeting; HPMC; X-ray imaging; microsponges (MS); pectin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colo / Neoplasias do Colo / Fluoruracila Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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