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Impact of the catechol-O-methyltransferase Val158Met polymorphism on the pharmacokinetics of L-dopa and its metabolite 3-O-methyldopa in combination with entacapone.
Yamamoto, Joe; Omura, Tomohiro; Kasamo, Sachiko; Yamamoto, Shota; Kawata, Masayoshi; Yonezawa, Atsushi; Taruno, Yosuke; Endo, Hisako; Aizawa, Hitoshi; Sawamoto, Nobukatsu; Matsubara, Kazuo; Takahashi, Ryosuke; Tasaki, Yoshikazu.
Afiliação
  • Yamamoto J; Department of Hospital Pharmacy and Pharmacology, Asahikawa Medical University, Asahikawa, 078-8510, Japan.
  • Omura T; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Kasamo S; Department of Pharmacy, Kobe University Hospital, Kobe, 650-0017, Japan.
  • Yamamoto S; Institutional Research Office, Asahikawa Medical University, Asahikawa, 078-8510, Japan.
  • Kawata M; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Yonezawa A; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Taruno Y; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Endo H; Department of Neurology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Aizawa H; Division of Neurology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, 078-8510, Japan.
  • Sawamoto N; Division of Neurology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, 078-8510, Japan.
  • Matsubara K; Department of Neurology, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.
  • Takahashi R; Department of Neurology, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
  • Tasaki Y; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan.
J Neural Transm (Vienna) ; 128(1): 27-36, 2021 01.
Article em En | MEDLINE | ID: mdl-33136226
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Levodopa / Catecol O-Metiltransferase Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Levodopa / Catecol O-Metiltransferase Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article