Testis-sparing Surgery: A Single Institution Experience.
Urology
; 147: 192-198, 2021 01.
Article
em En
| MEDLINE
| ID: mdl-33137349
ABSTRACT
OBJECTIVE:
To demonstrate the safety and efficacy of testis-sparing surgery (TSS) in 2 specific circumstances small, nonpalpable masses suspected to be benign and masses suspicious for germ cell tumor in a solitary or functionally solitary testicle or bilateral disease.METHODS:
Our institutional review board-approved testicular cancer registry was reviewed for men who underwent inguinal exploration with intent for TSS (2013-2020). The attempted TSS and completed TSS groups were evaluated for differences using Student's t test for normally-distributed variables, chi-squared and Fisher's exact tests for proportions, and Wilcoxon rank-sum test for nonparametric variables.RESULTS:
TSS was attempted in 28 patients and completed in 14. TSS was completed only if intraoperative frozen section demonstrated benign disease, except for 1 patient with stage I seminoma and solitary testicle. Sensitivity and specificity of frozen section analysis was 100% and 93%, respectively. There were no significant differences in demographics between attempted vs completed TSS cohorts. Median tumor size was significantly smaller in the completed TSS cohort (1.0 cm vs 1.7 cm, P = .03). In patients with unilateral masses without history of testis cancer, the testis was successfully spared in 9 of 22 cases (41%). In patients with bilateral disease or germ cell tumor in solitary testis, the testis was spared in 5 of 6 cases (83%). At a median follow up of 12.2 months, all patients were alive, and 27 of 28 had no evidence of disease (96%).CONCLUSION:
TSS is safe and effective for small, benign masses and in the setting of bilateral disease or tumor in a solitary testis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Testiculares
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Orquiectomia
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Neoplasias Embrionárias de Células Germinativas
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Tratamentos com Preservação do Órgão
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Recidiva Local de Neoplasia
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Humans
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Male
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article