Oral involvement in mucormycosis. A retrospective study of 55 cases.
Enferm Infecc Microbiol Clin (Engl Ed)
; 2020 Nov 03.
Article
em En, Es
| MEDLINE
| ID: mdl-33158598
ABSTRACT
INTRODUCTION:
Mucormycosis with oral involvement (OIM) is a rare opportunistic and lethal mycosis, which has increased in the last decade and is generally associated with uncontrolled diabetes and neutropenia.METHODS:
A retrospective study of cases with OIM was carried out in a tertiary-care center. Mycological and histological examinations were performed, and the isolated organisms were identified by morphology and molecular biology.RESULTS:
Fifty-five OIM patients were included, with a median age of 38 years (61.8% males). The most frequent associated disease was type-2 diabetes mellitus (61%), followed by neutropenia due to acute lymphocytic leukemia (27%). The main presentation was palatal and mandibular ulcers (92.7%) and, to a lesser extent, gingival and lingual necrosis. The diagnosis was established by mycological and histopathological studies. The most frequent fungi isolated was Rhizopus arrhizus (67.2%).CONCLUSION:
OIM is a rapidly progressing disease, therefore, an early diagnosis and the proper control of predisposing factors is necessary, and consequently, contributing to improve the outcome of mucormycosis.
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Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
/
Screening_studies
Idioma:
En
/
Es
Ano de publicação:
2020
Tipo de documento:
Article