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Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy.
Shaw, Joseph; Gosain, Rajendra; Kalita, Monoj Mon; Foster, Toshana L; Kankanala, Jayakanth; Mahato, D Ram; Abas, Sonia; King, Barnabas J; Scott, Claire; Brown, Emma; Bentham, Matthew J; Wetherill, Laura; Bloy, Abigail; Samson, Adel; Harris, Mark; Mankouri, Jamel; Rowlands, David J; Macdonald, Andrew; Tarr, Alexander W; Fischer, Wolfgang B; Foster, Richard; Griffin, Stephen.
Afiliação
  • Shaw J; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Gosain R; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Kalita MM; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Foster TL; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Kankanala J; Institute of Biophotonics, National Yang-Ming University, Taipei, Taiwan.
  • Mahato DR; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Abas S; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • King BJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Scott C; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Brown E; Institute of Biophotonics, National Yang-Ming University, Taipei, Taiwan.
  • Bentham MJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Wetherill L; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Bloy A; School of Life Sciences, Faculty of Medicine & Health Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom.
  • Samson A; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Harris M; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Mankouri J; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Rowlands DJ; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Macdonald A; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Tarr AW; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Fischer WB; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
  • Foster R; Astbury Centre for Structural Molecular Biology, University of Leeds, Woodhouse Lane, Leeds, United Kingdom.
  • Griffin S; Leeds Institute of Medical Research, School of Medicine, Faculty of Medicine and Health, University of Leeds, St James' University Hospital, Leeds, United Kingdom.
Elife ; 92020 11 10.
Article em En | MEDLINE | ID: mdl-33169665
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas Virais / Hepacivirus Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Proteínas Virais / Hepacivirus Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article