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Production of gene-edited pigs harboring orthologous human mutations via double cutting by CRISPR/Cas9 with long single-stranded DNAs as homology-directed repair templates by zygote injection.
Xie, Fei; Zhou, Xiaoyang; Lin, Tingting; Wang, Lulu; Liu, Chuanhong; Luo, Xi; Luo, Lihua; Chen, Huayu; Guo, Kenan; Wei, Hong; Wang, Yong.
Afiliação
  • Xie F; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Zhou X; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Lin T; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Wang L; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Liu C; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Luo X; Department of Foreign Languages Studies, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Luo L; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Chen H; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Guo K; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China.
  • Wei H; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China. weihong63528@163.com.
  • Wang Y; Department of Laboratory Animal Science, College of Basic Medical Sciences, Army Medical University, Third Military Medical University, Chongqing, 400038, China. yongw7528@hotmail.com.
Transgenic Res ; 29(5-6): 587-598, 2020 12.
Article em En | MEDLINE | ID: mdl-33170439
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porco Miniatura / Animais Geneticamente Modificados / Conexina 26 / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Porco Miniatura / Animais Geneticamente Modificados / Conexina 26 / Mutação Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article