Regulation of peroxisome proliferator-activated receptor-gamma activity affects the hepatic stellate cell activation and the progression of NASH via TGF-ß1/Smad signaling pathway.

Ni, Xi-Xi; Li, Xiao-Yun; Wang, Qi; Hua, Jing

Ni, Xi-Xi; Li, Xiao-Yun; Wang, Qi; Hua, Jing.

Afiliação

Ni XX; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pu Jian Road, Shanghai, 200127, People's Republic of China.
Li XY; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pu Jian Road, Shanghai, 200127, People's Republic of China.
Wang Q; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pu Jian Road, Shanghai, 200127, People's Republic of China.
Hua J; Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pu Jian Road, Shanghai, 200127, People's Republic of China. hua_jing88@163.com.

J Physiol Biochem ; 77(1): 35-45, 2021 Feb.

Article em En | MEDLINE | ID: mdl-33188625

Assuntos

Cirrose Hepática/metabolismo; Hepatopatia Gordurosa não Alcoólica/metabolismo; PPAR gama/fisiologia; Fator de Crescimento Transformador beta1/metabolismo; Animais; Células Estreladas do Fígado; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Células NIH 3T3; Transdução de Sinais; Proteína Smad2/metabolismo; Proteína Smad3/metabolismo

Palavras-chave

Hepatic stellate cell activation; Liver fibrosis; Nonalcoholic steatohepatitis; Peroxisome proliferator-activated receptor-gamma; TGF-ß1/Smad

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: PPAR gama / Fator de Crescimento Transformador beta1 / Hepatopatia Gordurosa não Alcoólica / Cirrose Hepática Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google