Cytogenetic and molecular genetic methods for chromosomal translocations detection with reference to the <i>KMT2A/MLL</i> gene.

Lomov, Nikolai; Zerkalenkova, Elena; Lebedeva, Svetlana; Viushkov, Vladimir; Rubtsov, Mikhail A

Cytogenetic and molecular genetic methods for chromosomal translocations detection with reference to the KMT2A/MLL gene.

Lomov, Nikolai; Zerkalenkova, Elena; Lebedeva, Svetlana; Viushkov, Vladimir; Rubtsov, Mikhail A.

Afiliação

Lomov N; Department of Molecular Biology, Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia.
Zerkalenkova E; Laboratory of Cytogenetics and Molecular Genetics Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Lebedeva S; Laboratory of Cytogenetics and Molecular Genetics Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia.
Viushkov V; Department of Molecular Biology, Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia.
Rubtsov MA; Department of Molecular Biology, Faculty of Biology, M.V. Lomonosov Moscow State University, Moscow, Russia.

Crit Rev Clin Lab Sci ; 58(3): 180-206, 2021 05.

Article em En | MEDLINE | ID: mdl-33205680

Assuntos

Proteína de Leucina Linfoide-Mieloide; Translocação Genética; Histona-Lisina N-Metiltransferase/genética; Humanos; Hibridização in Situ Fluorescente; Biologia Molecular; Proteína de Leucina Linfoide-Mieloide/genética; Translocação Genética/genética

Palavras-chave

Acute leukemia; KMT2A/MLL; MRD monitoring; chromosomal translocations detection; cytogenetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Translocação Genética / Proteína de Leucina Linfoide-Mieloide Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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