A pre-conditioning protocol of peripheral blood derived endothelial colony forming cells for endothelialization of tissue engineered constructs.

Kraus, Xenia; Pflaum, Michael; Thoms, Stefanie; Jonczyk, Rebecca; Witt, Martin; Scheper, Thomas; Blume, Cornelia

Kraus, Xenia; Pflaum, Michael; Thoms, Stefanie; Jonczyk, Rebecca; Witt, Martin; Scheper, Thomas; Blume, Cornelia.

Afiliação

Kraus X; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany. Electronic address: kraus@iftc.uni-hannover.de.
Pflaum M; Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, 30625 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
Thoms S; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
Jonczyk R; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
Witt M; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
Scheper T; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.
Blume C; Leibniz University Hannover, Institute of Technical Chemistry, Callinstr. 5, D-30167 Hannover, Germany; Lower Saxony Centre for Biomedical Engineering, Implant Research and Development (NIFE), 30625 Hannover, Germany.

Microvasc Res ; 134: 104107, 2021 03.

Article em En | MEDLINE | ID: mdl-33212112

Assuntos

Células Progenitoras Endoteliais/fisiologia; Células Endoteliais da Veia Umbilical Humana/fisiologia; Mecanotransdução Celular; Fluxo Pulsátil; Engenharia Tecidual; Antígenos CD/metabolismo; Reatores Biológicos; Antígeno CD146/metabolismo; Caderinas/metabolismo; Técnicas de Cultura de Células/instrumentação; Forma Celular; Células Cultivadas; Células Progenitoras Endoteliais/metabolismo; Feminino; Glucose/metabolismo; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Masculino; Pessoa de Meia-Idade; Neovascularização Fisiológica; Fenótipo; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Estresse Mecânico; Trombomodulina/genética; Trombomodulina/metabolismo

Palavras-chave

Actin cytoskeleton; Bioreactor culture; Endothelial colony-forming cells (ECFC); Endothelial progenitor cells (EPC); Endothelialization; Pulsatile flow; Thrombomodulin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fluxo Pulsátil / Engenharia Tecidual / Mecanotransdução Celular / Células Endoteliais da Veia Umbilical Humana / Células Progenitoras Endoteliais Tipo de estudo: Guideline Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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