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Toward a theory-based specification of non-pharmacological treatments in aging and dementia: Focused reviews and methodological recommendations.
Sikkes, Sietske A M; Tang, Yi; Jutten, Roos J; Wesselman, Linda M P; Turkstra, Lyn S; Brodaty, Henry; Clare, Linda; Cassidy-Eagle, Erin; Cox, Kay L; Chételat, Gaël; Dautricourt, Sophie; Dhana, Klodian; Dodge, Hiroko; Dröes, Rose-Marie; Hampstead, Benjamin M; Holland, Thomas; Lampit, Amit; Laver, Kate; Lutz, Antoine; Lautenschlager, Nicola T; McCurry, Susan M; Meiland, Franka J M; Morris, Martha Clare; Mueller, Kimberly D; Peters, Ruth; Ridel, Gemma; Spector, Aimee; van der Steen, Jenny T; Tamplin, Jeanette; Thompson, Zara; Bahar-Fuchs, Alex.
Afiliação
  • Sikkes SAM; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.
  • Tang Y; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands.
  • Jutten RJ; Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Disorders, Beijing, China.
  • Wesselman LMP; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.
  • Turkstra LS; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands.
  • Brodaty H; Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam University Medical Center, VU University Amsterdam, Amsterdam, the Netherlands.
  • Clare L; Department of Clinical, Neuro- and Developmental Psychology, VU University, Amsterdam, the Netherlands.
  • Cassidy-Eagle E; School of Rehabilitation Science, McMaster University, Hamilton, Ontario, Canada.
  • Cox KL; Centre for Healthy Brain Ageing and Dementia Centre for Research Collaboration, School of Psychiatry, UNSW, Sydney, Australia.
  • Chételat G; Centre for Research in Ageing and Cognitive Health, College of Medicine and Health, University of Exeter, Exeter, UK.
  • Dautricourt S; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California, USA.
  • Dhana K; Medical School, University of Western Australia, Perth, Western Australia, Australia.
  • Dodge H; Normandie Univ, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders,", Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France.
  • Dröes RM; Normandie Univ, UNICAEN, INSERM, U1237, PhIND "Physiopathology and Imaging of Neurological Disorders,", Institut Blood and Brain @ Caen-Normandie, Cyceron, Caen, France.
  • Hampstead BM; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA.
  • Holland T; Department of Neurology, Oregon Health and Science University, Portland, Oregon, USA.
  • Lampit A; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
  • Laver K; Department of Psychiatry, Amsterdam University Medical Center, VUmc, Amsterdam, the Netherlands.
  • Lutz A; Department of Psychiatry, University of Michigan and VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
  • Lautenschlager NT; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA.
  • McCurry SM; Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia.
  • Meiland FJM; Department of Rehabilitation, Aged and Extended Care, College of Medicine and Public Health, Flinders University, Adelaide, Australia.
  • Morris MC; Lyon Neuroscience Research Center INSERM U1028, CNRS UMR5292, Lyon University, Lyon, France.
  • Mueller KD; Academic Unit for Psychiatry of Old Age, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia.
  • Peters R; NorthWestern Mental Health, Melbourne Health, Melbourne, Australia.
  • Ridel G; Department of Child, Family, and Population Health Nursing, University of Washington, Seattle, Washington, USA.
  • Spector A; Department of Psychiatry, Amsterdam University Medical Center, VUmc, Amsterdam, the Netherlands.
  • van der Steen JT; Section on Nutrition and Nutritional Epidemiology, Department of Internal Medicine, Rush University, Chicago, Illinois, USA.
  • Tamplin J; Wisconsin Alzheimer's Institute, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin, USA.
  • Thompson Z; Department of Psychology, University of New South Wales, Randwick, Sydney, Australia.
  • Bahar-Fuchs A; The University of East Anglia, Norwich, UK.
Alzheimers Dement ; 17(2): 255-270, 2021 02.
Article em En | MEDLINE | ID: mdl-33215876
ABSTRACT

INTRODUCTION:

Non-pharmacological treatments (NPTs) have the potential to improve meaningful outcomes for older people at risk of, or living with dementia, but research often lacks methodological rigor and continues to produce mixed results.

METHODS:

In the current position paper, experts in NPT research have specified treatment targets, aims, and ingredients using an umbrella framework, the Rehabilitation Treatment Specification System.

RESULTS:

Experts provided a snapshot and an authoritative summary of the evidence for different NPTs based on the best synthesis efforts, identified main gaps in knowledge and relevant barriers, and provided directions for future research. Experts in trial methodology provide best practice principles and recommendations for those working in this area, underscoring the importance of prespecified protocols.

DISCUSSION:

We conclude that the evidence strongly supports various NPTs in relation to their primary targets, and discuss opportunities and challenges associated with a unifying theoretical framework to guide future efforts in this area.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Demência Tipo de estudo: Guideline / Qualitative_research Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Demência Tipo de estudo: Guideline / Qualitative_research Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article