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Multi-institutional Survey of Squamous Cell Carcinoma of the External Auditory Canal in Japan.
Shiga, Kiyoto; Nibu, Ken-Ichi; Fujimoto, Yasushi; Asakage, Takahiro; Homma, Akihiro; Mitani, Hiroki; Ogawa, Takenori; Okami, Kenji; Murono, Shigeyuki; Hirano, Shigeru; Ueda, Tsutomu; Hanai, Nobuhiro; Tsukahara, Kiyoaki; Ota, Ichiro; Yoshimoto, Seiichi; Shinozaki, Takeshi; Iwae, Shigemichi; Katagiri, Katsunori; Saito, Daisuke; Kiyota, Naomi; Tahara, Makoto; Takahashi, Fumiaki; Hayashi, Ryuichi.
Afiliação
  • Shiga K; Department of Head and Neck Surgery, Iwate Medical University School of Medicine, Yahaba, Japan.
  • Nibu KI; Department of Otolaryngology-Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
  • Fujimoto Y; Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Asakage T; Department of Head and Neck Surgery, Tokyo Medical and Dental University, Bunkyo-ku, Japan.
  • Homma A; Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
  • Mitani H; Department of Head and Neck Surgery, Cancer Institute Hospital of JFCR, Tokyo, Japan.
  • Ogawa T; Department of Otolaryngology-Head and Neck Surgery, Tohoku University Hospital, Sendai, Japan.
  • Okami K; Department of Otolaryngology, Tokai University School of Medicine, Hiratsuka, Japan.
  • Murono S; Department of Otolaryngology, Fukushima Medical University, Fukushima, Japan.
  • Hirano S; Department of Otolaryngology-Head and Neck Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
  • Ueda T; Department of Otorhinolaryngology-Head and Neck Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima, Japan.
  • Hanai N; Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Tsukahara K; Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Shinjuku-ku, Japan.
  • Ota I; Department of Otolaryngology-Head and Neck Surgery, Nara Medical University, Kashihara, Japan.
  • Yoshimoto S; Department of Head and Neck Surgery, National Cancer Center Hospital, Tokyo, Japan.
  • Shinozaki T; Department of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa, Japan.
  • Iwae S; Department of Head and Neck Surgery, Hyogo Cancer Center, Akashi, Japan.
  • Katagiri K; Department of Head and Neck Surgery, Iwate Medical University School of Medicine, Yahaba, Japan.
  • Saito D; Department of Head and Neck Surgery, Iwate Medical University School of Medicine, Yahaba, Japan.
  • Kiyota N; Department of Medical Oncology/Hematology, Kobe University Hospital Cancer Center, Kobe, Japan.
  • Tahara M; Department of Head and Neck Medical Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Takahashi F; Division of Medical Engineering, Department of Information Science, Iwate Medical University, Yahaba, Japan.
  • Hayashi R; Department of Head and Neck Surgery, National Cancer Center Hospital East, Kashiwa, Japan.
Laryngoscope ; 131(3): E870-E874, 2021 03.
Article em En | MEDLINE | ID: mdl-33216374
OBJECTIVES: This study aimed to evaluate the efficacy of chemoradiotherapy (CRT) for patients with advanced cancer of the external auditory canal (EAC) by analyzing the outcome of the patients. METHODS: This is a multi-institutional retrospective survey, and we reviewed the medical records of the subjects. A total of 181 patients with tumor (T)3 or T4 tumor in 17 institutions were enrolled. Further analysis was performed for 74 patients who underwent CRT under curative intent. RESULTS: Overall 5-year survival rates of the patients who underwent CRT (n = 74) were 54.6%. Those of the patients who underwent CRT with modified TPF (docetaxel, cisplatin [CDDP], and 5-fluorouracil) regimen (n = 50) and CRT with CDDP regimens (n = 24) were 64.4% and 36.7%, respectively. Significant differences were observed between these two groups. CONCLUSION: Given the tendency that head and neck surgeons prefer CRT for advanced larger cancer of the EAC, CRT for advanced EAC cancer using the modified TPF regimen showed good clinical outcomes. LEVEL OF EVIDENCE: 4 Laryngoscope, 131:E870-E874, 2021.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Neoplasias da Orelha / Carcinoma de Células Escamosas / Protocolos de Quimioterapia Combinada Antineoplásica / Meato Acústico Externo / Quimiorradioterapia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans País como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Padrões de Prática Médica / Neoplasias da Orelha / Carcinoma de Células Escamosas / Protocolos de Quimioterapia Combinada Antineoplásica / Meato Acústico Externo / Quimiorradioterapia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans País como assunto: Asia Idioma: En Ano de publicação: 2021 Tipo de documento: Article