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Targeting Nestin+ hepatic stellate cells ameliorates liver fibrosis by facilitating TßRI degradation.
Chen, Huaxin; Cai, Jianye; Wang, Jiancheng; Qiu, Yuan; Jiang, Chenhao; Wang, Yi; Wang, Yiqin; Yi, Chenju; Pan, Lijie; Guan, Yuanjun; Zheng, Jun; Qiu, Dongbo; Du, Cong; Liu, Qiuli; Chen, Guihua; Yang, Yang; Xu, Yan; Xiang, Andy Peng; Zhang, Qi.
Afiliação
  • Chen H; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Cell-gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Cai J; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China; Department of Hepatic Surgery and Liver Transplantation Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou
  • Wang J; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China; Scientific Research Centre, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
  • Qiu Y; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Jiang C; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Wang Y; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Wang Y; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China.
  • Yi C; Scientific Research Centre, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China.
  • Guo Lv; Department of Hepatic Surgery and Liver Transplantation Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Pan L; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Cell-gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Guan Y; Core Facility Centre, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Zheng J; Department of Hepatic Surgery and Liver Transplantation Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Qiu D; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Cell-gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Liver Disease Research, The Third Affi
  • Du C; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Cell-gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Liver Disease Research, The Third Affi
  • Liu Q; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Chen G; Department of Hepatic Surgery and Liver Transplantation Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Yang Y; Department of Hepatic Surgery and Liver Transplantation Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address: yysysu@163.com.
  • Xu Y; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. Electronic address: xuyan55@mail.sysu.edu.cn.
  • Xiang AP; Centre for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, China. Electronic address: xiangp@mail.sysu.edu.cn.
  • Zhang Q; Biotherapy Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Cell-gene Therapy Translational Medicine Research Centre, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Liver Disease Research, The Third Affi
J Hepatol ; 74(5): 1176-1187, 2021 05.
Article em En | MEDLINE | ID: mdl-33217494
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Proteína Smad2 / Proteína Smad3 / Nestina / Receptor do Fator de Crescimento Transformador beta Tipo I / Cirrose Hepática Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Proteína Smad2 / Proteína Smad3 / Nestina / Receptor do Fator de Crescimento Transformador beta Tipo I / Cirrose Hepática Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article