Synthetic peptides against Trichophyton mentagrophytes and T. rubrum: Mechanisms of action and efficiency compared to griseofulvin and itraconazole.

Lima, Patrícia G; Souza, Pedro F N; Freitas, Cleverson D T; Bezerra, Leandro P; Neto, Nilton A S; Silva, Ayrles F B; Oliveira, Jose T A; Sousa, Daniele O B

Lima, Patrícia G; Souza, Pedro F N; Freitas, Cleverson D T; Bezerra, Leandro P; Neto, Nilton A S; Silva, Ayrles F B; Oliveira, Jose T A; Sousa, Daniele O B.

Afiliação

Lima PG; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Souza PFN; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil. Electronic address: pedrofilhobio@gmail.com.
Freitas CDT; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Bezerra LP; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Neto NAS; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Silva AFB; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Oliveira JTA; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil.
Sousa DOB; Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza, Ceará CEP 60.440-554, Brazil. Electronic address: daniele.sousa@ufc.br.

Life Sci ; 265: 118803, 2021 Jan 15.

Article em En | MEDLINE | ID: mdl-33238167

Assuntos

Antifúngicos/farmacologia; Arthrodermataceae/efeitos dos fármacos; Griseofulvina/farmacologia; Itraconazol/farmacologia; Fragmentos de Peptídeos/farmacologia; Antifúngicos/síntese química; Arthrodermataceae/fisiologia; Técnicas de Química Sintética; Griseofulvina/síntese química; Humanos; Itraconazol/síntese química; Fragmentos de Peptídeos/síntese química

Palavras-chave

Dermatophytes; Griseofulvin; Itraconazole; Synthetic antifungal peptides; Synthetic peptides

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Itraconazol / Arthrodermataceae / Griseofulvina / Antifúngicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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