Overhydration and low serum prealbumin predict peritoneal dialysis-related peritonitis in continuous ambulatory peritoneal dialysis patients.
BMC Nephrol
; 21(1): 512, 2020 11 25.
Article
em En
| MEDLINE
| ID: mdl-33238904
ABSTRACT
BACKGROUND:
In this study, we focused on the role of overhydration (OH) and low serum prealbumin concentration in predicting peritonitis in continuous ambulatory peritoneal dialysis (CAPD) patients over a 3-year period.METHODS:
We measured serum prealbumin concentration and OH by body composition monitor in 278 CAPD patients (159 males and 119 females) with a mean age of 46 years and a median peritoneal dialysis (PD) duration of 21 months. Cases of PD-related peritonitis were collected over 3 years.RESULTS:
After the 3-year follow-up, 44 patients were diagnosed with PD-related peritonitis (15.8%). Low education, serum glucose, prealbumin, and OH were independent risk factors for predicting peritonitis over 36 months in CAPD patients. Based on the ROC curve model and Kaplan-Meier analysis, we realized that low prealbumin and high OH were independent predictors of 3-year peritonitis in CAPD patients (Prealbumin AUC = 0.838, cut-off value = 32.5 mg/dL, Se = 90.9%, Sp = 32.9%; OH AUC = 0.851, cut-off value = 1.33 L, Se = 79.5%, Sp = 85.5%; and log-rank test p < 0.001, respectively).CONCLUSION:
Overhydration and low serum prealbumin were the independent predictors of PD-related peritonitis in CAPD patients.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Peritonite
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Desequilíbrio Hidroeletrolítico
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Pré-Albumina
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Diálise Peritoneal Ambulatorial Contínua
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article