A colorimetric sensing strategy based on enzyme@metal-organic framework and oxidase-like IrO<sub>2</sub>/MnO<sub>2</sub> nanocomposite for &#945;-glucosidase inhibitor screening.

Zhong, Yingying; Li, Qing-Lan; Lu, Minglei; Wang, Tiantian; Yang, Huiyi; He, Qiyi; Cui, Xiping; Li, Xiangguang; Zhao, Suqing

A colorimetric sensing strategy based on enzyme@metal-organic framework and oxidase-like IrO₂/MnO₂ nanocomposite for α-glucosidase inhibitor screening.

Zhong, Yingying; Li, Qing-Lan; Lu, Minglei; Wang, Tiantian; Yang, Huiyi; He, Qiyi; Cui, Xiping; Li, Xiangguang; Zhao, Suqing.

Afiliação

Zhong Y; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Li QL; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Lu M; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Wang T; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Yang H; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
He Q; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China.
Cui X; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China. cuixiping1989@163.com.
Li X; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China. xgl@gdut.edu.cn.
Zhao S; Department of Pharmaceutical Engineering, School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, 510006, People's Republic of China. sqzhao@gdut.edu.cn.

Mikrochim Acta ; 187(12): 675, 2020 11 25.

Article em En | MEDLINE | ID: mdl-33241461

Assuntos

Colorimetria/métodos; Inibidores de Glicosídeo Hidrolases/análise; Estruturas Metalorgânicas/química; Nanocompostos/química; alfa-Glucosidases/metabolismo; Acarbose/análise; Ácido Ascórbico/análise; Catálise; Enzimas Imobilizadas/química; Enzimas Imobilizadas/metabolismo; Irídio/química; Limite de Detecção; Compostos de Manganês/química; Óxidos/química; alfa-Glucosidases/química

Palavras-chave

Colorimetric method; GAA inhibitors screening; GAA@Cu-MOF reactor; IrO2/MnO2 nanocomposite; Oxidase-like activity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colorimetria / Alfa-Glucosidases / Nanocompostos / Inibidores de Glicosídeo Hidrolases / Estruturas Metalorgânicas Tipo de estudo: Diagnostic_studies / Screening_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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