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Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Chong, Stephen Jun Fei; Iskandar, Kartini; Lai, Jolin Xiao Hui; Qu, Jianhua; Raman, Deepika; Valentin, Rebecca; Herbaux, Charles; Collins, Mary; Low, Ivan Cherh Chiet; Loh, Thomas; Davids, Matthew; Pervaiz, Shazib.
Afiliação
  • Chong SJF; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Iskandar K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lai JXH; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Qu J; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Raman D; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Valentin R; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Herbaux C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Collins M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Low ICC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Loh T; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore, Singapore.
  • Davids M; Department of Otolaryngology, National University of Healthcare System (NUHS), Singapore, Singapore.
  • Pervaiz S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Nucleic Acids Res ; 48(22): 12727-12745, 2020 12 16.
Article em En | MEDLINE | ID: mdl-33245769
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Estresse Oxidativo / Proteínas Proto-Oncogênicas c-bcl-2 / Linfoma / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Estresse Oxidativo / Proteínas Proto-Oncogênicas c-bcl-2 / Linfoma / Mitocôndrias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article