Adrenomedullin 2 attenuates LPS-induced inflammation in microglia cells by receptor-mediated cAMP-PKA pathway.

Sun, Jing; Qian, Pei; Kang, Ying; Dai, Hang-Bing; Wang, Fang-Zheng; Wang, Hong-Yu; Zhou, Hong; Gao, Qing; Zhou, Ye-Bo

Sun, Jing; Qian, Pei; Kang, Ying; Dai, Hang-Bing; Wang, Fang-Zheng; Wang, Hong-Yu; Zhou, Hong; Gao, Qing; Zhou, Ye-Bo.

Afiliação

Sun J; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Qian P; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Kang Y; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Dai HB; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Wang FZ; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Wang HY; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Zhou H; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Gao Q; Department of Physiology, Nanjing Medical University, Nanjing 211166, China.
Zhou YB; Department of Physiology, Nanjing Medical University, Nanjing 211166, China. Electronic address: zhouyebo666@njmu.edu.cn.

Neuropeptides ; 85: 102109, 2021 Feb.

Article em En | MEDLINE | ID: mdl-33253929

Assuntos

Inflamação/metabolismo; Microglia/metabolismo; Transdução de Sinais; Animais; Células Cultivadas; AMP Cíclico/metabolismo; Proteínas Quinases Dependentes de AMP Cíclico/metabolismo; Mediadores da Inflamação/metabolismo; Lipopolissacarídeos/administração & dosagem; Ratos Sprague-Dawley; Receptores de AMP Cíclico/metabolismo

Palavras-chave

Adrenomedullin 2; Adrenomedullin receptor; Inflammation; Microglia; Protein kinase A; Receptor activity-modifying proteins

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Microglia / Inflamação Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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