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The Aerogen® Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin.
Dallas, Ronald H; Rains, Jason K; Wilder, Keith; Humphrey, William; Cross, Shane J; Ghafoor, Saad; Brazelton de Cardenas, Jessica N; Hayden, Randall T; Hijano, Diego R.
Afiliação
  • Dallas RH; Department of Infectious Diseases, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Rains JK; Department of Critical Care and Pulmonary Medicine, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Wilder K; Department of Critical Care and Pulmonary Medicine, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Humphrey W; Department of Pharmaceutical Sciences, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Cross SJ; Department of Pharmaceutical Sciences, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Ghafoor S; Department of Critical Care and Pulmonary Medicine, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Brazelton de Cardenas JN; Department of Pathology, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Hayden RT; Department of Pathology, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
  • Hijano DR; Department of Infectious Diseases, St. Jude Children Research Hospital, Memphis, TN 38105, USA.
Pharmaceutics ; 12(12)2020 Nov 29.
Article em En | MEDLINE | ID: mdl-33260359
Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen®). We did not observe any adverse events with this method.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2020 Tipo de documento: Article