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Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
Krumpe, Lauren R H; Wilson, Brice A P; Marchand, Christophe; Sunassee, Suthananda N; Bermingham, Alun; Wang, Wenjie; Price, Edmund; Guszczynski, Tad; Kelley, James A; Gustafson, Kirk R; Pommier, Yves; Rosengren, K Johan; Schroeder, Christina I; O'Keefe, Barry R.
Afiliação
  • Krumpe LRH; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States.
  • Wilson BAP; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Marchand C; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Sunassee SN; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, NCI, NIH, Bethesda, Maryland 20892, United States.
  • Bermingham A; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Wang W; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Price E; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, NCI, NIH, Bethesda, Maryland 20892, United States.
  • Guszczynski T; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Kelley JA; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Gustafson KR; Chemical Biology Laboratory, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Pommier Y; Molecular Targets Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
  • Rosengren KJ; Developmental Therapeutics Branch, Laboratory of Molecular Pharmacology, NCI, NIH, Bethesda, Maryland 20892, United States.
  • Schroeder CI; School of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
  • O'Keefe BR; Chemical Biology Laboratory, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, United States.
J Am Chem Soc ; 142(50): 21178-21188, 2020 12 16.
Article em En | MEDLINE | ID: mdl-33263997
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Tirosina / Diester Fosfórico Hidrolases / Inibidores Enzimáticos Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Tirosina / Diester Fosfórico Hidrolases / Inibidores Enzimáticos Idioma: En Ano de publicação: 2020 Tipo de documento: Article