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The tale of proteolysis targeting chimeras (PROTACs) for Leucine-Rich Repeat Kinase 2 (LRRK2).
Konstantinidou, Markella; Oun, Asmaa; Pathak, Pragya; Zhang, Bidong; Wang, Zefeng; Ter Brake, Frans; Dolga, Amalia M; Kortholt, Arjan; Dömling, Alexander.
Afiliação
  • Konstantinidou M; Department of Pharmacy, Group of Drug Design, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Oun A; Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy (GRIP), University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Pathak P; Department of Cell Biochemistry, Groningen Institute of Biomolecular Sciences & Biotechnology, University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.
  • Zhang B; Department of Pharmacy, Group of Drug Design, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Wang Z; Department of Pharmacy, Group of Drug Design, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Ter Brake F; Department of Pharmacy, Group of Drug Design, University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Dolga AM; Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy (GRIP), University of Groningen, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Kortholt A; Department of Cell Biochemistry, Groningen Institute of Biomolecular Sciences & Biotechnology, University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.
  • Dömling A; YETEM-Innovative Technologies Application and Research Centre Suleyman Demirel University, West Campus, 32260, Isparta, Turkey.
ChemMedChem ; 16(6): 959-965, 2021 03 18.
Article em En | MEDLINE | ID: mdl-33278061

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirróis / Inibidores de Proteínas Quinases / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirróis / Inibidores de Proteínas Quinases / Serina-Treonina Proteína Quinase-2 com Repetições Ricas em Leucina Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article