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Enhancer II-targeted dsRNA decreases GDNF expression via histone H3K9 trimethylation to inhibit glioblastoma progression.
Zhang, Baole; Han, Xiao; Gao, Qing; Liu, Jie; Li, Saisai; Zha, Wei; Wang, Xiaoyu; Guo, Xiaoxiao; Gao, Dianshuai.
Afiliação
  • Zhang B; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China. Electronic address: zbl@xzhmu.edu.cn.
  • Han X; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Gao Q; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Liu J; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Li S; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Zha W; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Wang X; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Guo X; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China.
  • Gao D; Department of Neurobiology and Anatomy, Xuzhou Key Laboratory of Neurobiology, Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, Jiangsu Province, China. Electronic address: gds@xzhmu.edu.cn.
Brain Res Bull ; 167: 22-32, 2021 02.
Article em En | MEDLINE | ID: mdl-33278485
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / RNA de Cadeia Dupla / Glioblastoma / Fator Neurotrófico Derivado de Linhagem de Célula Glial / Técnicas de Silenciamento de Genes Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / RNA de Cadeia Dupla / Glioblastoma / Fator Neurotrófico Derivado de Linhagem de Célula Glial / Técnicas de Silenciamento de Genes Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article