Alkoxylalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities.

Onwubiko, Nichodemus O; Diaz, Suraya A; Krecmerová, Marcela; Nasheuer, Heinz Peter

Onwubiko, Nichodemus O; Diaz, Suraya A; Krecmerová, Marcela; Nasheuer, Heinz Peter.

Afiliação

Onwubiko NO; Biochemistry, School of Natural Science and Centre for Chromosome Biology, NUI Galway, Galway, Ireland.
Diaz SA; Biochemistry, School of Natural Science and Centre for Chromosome Biology, NUI Galway, Galway, Ireland.
Krecmerová M; Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, Prague, Czech Republic.
Nasheuer HP; Biochemistry, School of Natural Science and Centre for Chromosome Biology, NUI Galway, Galway, Ireland heinz.nasheuer@nuigalway.ie.

Antimicrob Agents Chemother ; 65(3)2021 02 17.

Article em En | MEDLINE | ID: mdl-33288638

Assuntos

Antígenos Virais de Tumores; Polyomavirus; Citosina; Replicação do DNA; DNA Viral/genética; Ésteres/farmacologia; Humanos; Nucleotídeos; Polyomavirus/genética; Replicação Viral

Palavras-chave

ATPase; DNA helicase; DNA replication; large T antigen; nucleoside analogs; polyomavirus; protein-DNA interactions

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polyomavirus / Antígenos Virais de Tumores Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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