On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment.

Longo, Liam M; Jablonska, Jagoda; Vyas, Pratik; Kanade, Manil; Kolodny, Rachel; Ben-Tal, Nir; Tawfik, Dan S

Longo, Liam M; Jablonska, Jagoda; Vyas, Pratik; Kanade, Manil; Kolodny, Rachel; Ben-Tal, Nir; Tawfik, Dan S.

Afiliação

Longo LM; Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel.
Jablonska J; Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel.
Vyas P; Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel.
Kanade M; Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel.
Kolodny R; University of Haifa, Department of Computer Science, Haifa, Israel.
Ben-Tal N; Tel Aviv University, George S. Wise Faculty of Life Sciences, Department of Biochemistry and Molecular Biology, Tel Aviv, Israel.
Tawfik DS; Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel.

Elife ; 92020 12 09.

Article em En | MEDLINE | ID: mdl-33295875

Assuntos

Proteínas AAA/metabolismo; Proteínas AAA/química; Proteínas AAA/genética; Sítios de Ligação; Evolução Molecular; Estrutura Terciária de Proteína; Alinhamento de Sequência

Palavras-chave

P-loop; ancient peptide; enzyme evolution; evolutionary biology; last universal common ancestor; none; protein evolution

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas AAA Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas AAA Idioma: En Ano de publicação: 2020 Tipo de documento: Article