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A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug-Drug-Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine.
Kanacher, Tobias; Lindauer, Andreas; Mezzalana, Enrica; Michon, Ingrid; Veau, Celine; Mantilla, Jose David Gómez; Nock, Valerie; Fleury, Angèle.
Afiliação
  • Kanacher T; SGS-Exprimo, 2800 Mechelen, Belgium.
  • Lindauer A; SGS-Exprimo, 2800 Mechelen, Belgium.
  • Mezzalana E; SGS-Exprimo, 2800 Mechelen, Belgium.
  • Michon I; SGS-Exprimo, 2800 Mechelen, Belgium.
  • Veau C; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riß, Germany.
  • Mantilla JDG; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riß, Germany.
  • Nock V; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riß, Germany.
  • Fleury A; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397 Biberach an der Riß, Germany.
Pharmaceutics ; 12(12)2020 Dec 08.
Article em En | MEDLINE | ID: mdl-33302490
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article