On-Demand Radial Electrodeposition of Alginate Tubular Structures.
ACS Biomater Sci Eng
; 5(7): 3184-3189, 2019 Jul 08.
Article
em En
| MEDLINE
| ID: mdl-33304999
ABSTRACT
We present an electrodeposition technique for fabricating tubular alginate structures. In this technique, two electrodes (anode and cathode) are suspended in a solution of alginate and insoluble calcium carbonate particles, and the application of an electrical potential produces a localized pH change at the anode surface causing suspended divalent cations to become soluble and cross-link the alginate. We robustly characterize how the fabrication parameters influence the rate of radial deposition on the anode, including deposition time, applied voltage, alginate concentration, type of divalent cation and concentration, and anode diameter. Furthermore, we produce gels with a range of tailorable features, including mechanical properties, dimensions (thick-ness and lumen size), customizable tubular geometries, and radial compositional heterogeneity.
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MEDLINE
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Ano de publicação:
2019
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Article