Evaluation of imidazo[2,1-b]thiazole-based anticancer agents in one decade (2011-2020): Current status and future prospects.

Sbenati, Rawan M; Semreen, Mohammad H; Semreen, Ahlam M; Shehata, Mahmoud K; Alsaghir, Fai M; El-Gamal, Mohammed I

Sbenati, Rawan M; Semreen, Mohammad H; Semreen, Ahlam M; Shehata, Mahmoud K; Alsaghir, Fai M; El-Gamal, Mohammed I.

Afiliação

Sbenati RM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.
Semreen MH; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
Semreen AM; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
Shehata MK; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
Alsaghir FM; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates.
El-Gamal MI; Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mans

Bioorg Med Chem ; 29: 115897, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33316752

Assuntos

Antineoplásicos/química; Imidazóis/química; Inibidores de Proteínas Quinases/química; Tiazóis/química; Antineoplásicos/farmacologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Ensaios de Seleção de Medicamentos Antitumorais; Receptores ErbB/antagonistas & inibidores; Humanos; Modelos Moleculares; Ligação Proteica; Inibidores de Proteínas Quinases/farmacologia; Proteínas Quinases S6 Ribossômicas 90-kDa/antagonistas & inibidores; Transdução de Sinais; Relação Estrutura-Atividade; Tiazóis/farmacologia; Tubulina (Proteína)/metabolismo

Palavras-chave

Anticancer; Antiproliferative; Imidazo[2,1-b]thiazole; Imidazothiazole; Kinase inhibitor; Tubulin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tiazóis / Inibidores de Proteínas Quinases / Imidazóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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