Alveolar Soft Part Sarcoma of Uterine Corpus in a Young Female: A Case Report With Review of Literature.
Int J Gynecol Pathol
; 40(3): 272-277, 2021 May 01.
Article
em En
| MEDLINE
| ID: mdl-33323848
ABSTRACT
Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma, often occurs in adolescents and young adults with a particular predilection for the deep soft tissue of extremities. Occurrence of ASPS in the female genital tract is very uncommon and poses a significant diagnostic challenge. A case of ASPS of the uterine corpus is described in a young unmarried female, who presented to the out-patient clinic of our Institute with complaints of abnormal uterine bleeding for the past 9 mo. She was being treated with oral contraceptive pills, progesterone and tranexamic acid. Following radiological imaging and hysteroscopy, a therapeutic curettage of the lesion was done. The histopathologic features raised a differential diagnosis of a myriad of morphologic mimickers. The diagnosis was clinched by exclusion of mimickers by relevant immunohistochemical markers and strong nuclear expression of TFE3 on immunohistochemistry. The patient is on regular follow-up with oral contraceptives and antifibrinolytic medication. Despite being infrequent at this location, ASPS should be kept in differential diagnosis in young females presenting with abnormal uterine bleeding.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias de Tecidos Moles
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Hemorragia Uterina
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Sarcoma Alveolar de Partes Moles
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Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
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Female
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Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article