Hypertension and the roles of the 9p21.3 risk locus: Classic findings and new association data.

Gallo, Juan E; Ochoa, Juan E; Warren, Helen R; Misas, Elizabeth; Correa, Monica M; Gallo-Villegas, Jaime A; Bedoya, Gabriel; Aristizábal, Dagnóvar; McEwen, Juan G; Caulfield, Mark J; Parati, Gianfranco; Clay, Oliver K

Gallo, Juan E; Ochoa, Juan E; Warren, Helen R; Misas, Elizabeth; Correa, Monica M; Gallo-Villegas, Jaime A; Bedoya, Gabriel; Aristizábal, Dagnóvar; McEwen, Juan G; Caulfield, Mark J; Parati, Gianfranco; Clay, Oliver K.

Afiliação

Gallo JE; Cellular & Molecular Biology Unit, Corporación para Investigaciones Biológicas, Medellín, Colombia.
Ochoa JE; Doctoral Program in Biomedical Sciences, Universidad del Rosario, Bogotá, Colombia.
Warren HR; Cellular & Molecular Biology Unit, Corporación para Investigaciones Biológicas, Medellín, Colombia.
Misas E; Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy.
Correa MM; Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Gallo-Villegas JA; Clinical Pharmacology Department, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Bedoya G; National Institute for Health Research, Barts Cardiovascular Biomedical Research Center, Queen Mary University of London, London, UK.
Aristizábal D; Cellular & Molecular Biology Unit, Corporación para Investigaciones Biológicas, Medellín, Colombia.
McEwen JG; Institute of Biology, Universidad de Antioquia, Medellín, Colombia.
Caulfield MJ; SICOR, Medellín, Colombia.
Parati G; SICOR, Medellín, Colombia.
Clay OK; School of Medicine, Universidad de Antioquia, Medellín, Colombia.

Int J Cardiol Hypertens ; 7: 100050, 2020 Dec.

Article em En | MEDLINE | ID: mdl-33330845

Palavras-chave

1 KG, 1000 Genomes Project; BP, blood pressure; Blood pressure levels; CVD, cardiovascular disease; DBP, diastolic blood pressure; EGFR, epidermal growth factor receptor; GWAS, genome wide association studi(es); Genotype-phenotype associations; Haplotypes; MAF, minor allele frequency; RAS, renin angiotensin system; SBP, systolic blood pressure; SNP, single nucleotide polymorphism; TGF-ß, transforming growth factor beta; VSMC, vascular smooth muscle cell(s); bp, base pair; kb, kilobase pair

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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