Communication: The Follow-Up of Biomarkers Better Predicts the Poor Outcome in COVID-19 Patients.
Ann Clin Lab Sci
; 50(6): 848-851, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-33334804
ABSTRACT
OBJECTIVE:
To investigate the course of biomarkers on admission and follow-up in order to identify early predictors for poor outcome in COVID-19 patients.METHODS:
In this study, 132 COVID-19 patients were classified as good outcome (n=62) and poor outcome (n=70) groups. Laboratory parameters were evaluated on admission and within 5-7 days after hospitalization.RESULTS:
Baseline levels of neutrophil-lymphocyte ratio, CRP, procalcitonin, ferritin, D-dimer and LDH were higher (p<0.01); lymphocyte count was lower in the poor outcome patients. During follow-up there was a larger decrease in lymphocyte count and more prominent increases in other biomarkers (p<0.001). In ROC analysis, the AUCs strongly indicated the poor outcome on days 5-7 of the hospitalization.CONCLUSIONS:
This study suggests that the follow-up measurements of the biomarkers better predict the poor outcome in COVID-19 pneumonia.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Índice de Gravidade de Doença
/
Biomarcadores
/
SARS-CoV-2
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article