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Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide.
Jiang, Rongrong; Hart, Andrew; Burgess, Laurette; Kim, Dae-Shik; Lai, Weidong George; Dixit, Vaishali.
Afiliação
  • Jiang R; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.) Rongrong_jiang@eisai.com.
  • Hart A; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.).
  • Burgess L; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.).
  • Kim DS; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.).
  • Lai WG; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.).
  • Dixit V; Drug Metabolism and Pharmacokinetics (R.J., V.D., W.G.L., A.H.) and Genetics Guided Dementia Discovery, Eisai Inc, Cambridge, Massachusetts (L.B., D.-S.K.) dixitv77@gmail.com.
Drug Metab Dispos ; 49(3): 265-275, 2021 03.
Article em En | MEDLINE | ID: mdl-33355210
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Sistema Biliar / Compostos Macrocíclicos / Eliminação Hepatobiliar / Vias de Eliminação de Fármacos / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Sistema Biliar / Compostos Macrocíclicos / Eliminação Hepatobiliar / Vias de Eliminação de Fármacos / Fígado Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article