Comprehensive metabolism study of swertiamarin in rats using ultra high-performance liquid chromatography coupled with Quadrupole-Exactive Orbitrap mass spectrometry.

Ma, Beibei; Lou, Tianyu; Wang, Tingting; Li, Ruiji; Liu, Jinhui; Yu, Shangyue; Guo, Yudong; Wang, Zhibin; Wang, Jing

Ma, Beibei; Lou, Tianyu; Wang, Tingting; Li, Ruiji; Liu, Jinhui; Yu, Shangyue; Guo, Yudong; Wang, Zhibin; Wang, Jing.

Afiliação

Ma B; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Lou T; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Wang T; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Li R; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Liu J; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Yu S; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.
Guo Y; Beijing Institute for Drug Control, Beijing, China.
Wang Z; Beijing Tongrentang Research Institute, Beijing, China.
Wang J; School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China.

Xenobiotica ; 51(4): 455-466, 2021 Apr.

Article em En | MEDLINE | ID: mdl-33356745

Assuntos

Glucosídeos Iridoides; Espectrometria de Massas por Ionização por Electrospray; Animais; Cromatografia Líquida de Alta Pressão; Pironas; Ratos; Ratos Sprague-Dawley

Palavras-chave

Swertiamarin; UHPLC-Q-Exactive Orbitrap mass spectrometry; biotransformation process; metabolic profile; metabolites

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectrometria de Massas por Ionização por Electrospray / Glucosídeos Iridoides Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google