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The role of fentanyl in the treatment of breakthrough cancer pain: Different biotechnologies, different results and different drug costs.
Giuliani, Jacopo; Fiorica, Francesco; Sacchetto, Alfredo; Franceschini, Gianfranco; Vaccari, Ferdinando; Bonetti, Andrea.
Afiliação
  • Giuliani J; Department of Oncology, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
  • Fiorica F; Department of Radiation Oncology, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
  • Sacchetto A; Palliative Care Unit, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
  • Franceschini G; Palliative Care Unit, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
  • Vaccari F; Palliative Care Unit, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
  • Bonetti A; Department of Oncology, Mater Salutis Hospital, Scaligera, Legnago, VR, Italy.
J Oncol Pharm Pract ; 27(2): 445-447, 2021 Mar.
Article em En | MEDLINE | ID: mdl-33356990
The aim of this paper was to assess the drug costs of the different biotechnologies (intranasal fentanyl spray (INFS), oral transmucosal fentanyl citrate (OTFC) and fentanyl buccal tablet (FBT)) in the treatment of breakthrough cancer pain (BTCP). We have calculated the mean drug costs (expressed in euros (€)) for patients treated for BTCP. INFS resulted the less expensive towards OTFC and FBT, with 697 440 €versus (vs.) 809 552 €vs. 779 662 €every 100 patients treated for BTCP, respectively. In conclusion, combining drug costs of different biotechnologies (INFS, OTFC and FBT) with the measure of efficacy represented by the reduction of BTCP avoided (incremental cost-effectiveness ratio, ICER), INFS resulted in better cost-effectiveness.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fentanila / Custos de Medicamentos / Dor Irruptiva / Dor do Câncer / Analgésicos Opioides Tipo de estudo: Health_economic_evaluation Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fentanila / Custos de Medicamentos / Dor Irruptiva / Dor do Câncer / Analgésicos Opioides Tipo de estudo: Health_economic_evaluation Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article